CFTR Gene Mutations in Men with Bilateral Ejaculatory-Duct Obstruction and Anomalies of the Seminal Vesicles
نویسندگان
چکیده
منابع مشابه
I-2: Ejaculatory Duct Obstruction
Ejaculatory duct obstruction (EDO) underlies 1-5% of male infertility, although the diagnosis of EDO can be complex, treatment is well established and can be very effective. Part of reason that this condition probably is underdiagnosed, is because of its rarity, subtle presentation and the concomitantly low index of suspicion held by physicians. The causes of EDO are divided into congenital and...
متن کاملScreening of two closed mutations in CFTR gene of Iranian infertile men with non-obstructive azoospermia
Background The genetic association between cystic fibrosis transmembrane conductance regulator (CFTR) gene mutations and male infertility due to congenital bilateral absence of vas deferens (CBAVD) is well established. Mutant CFTR, however may also be involved in the etiology of male infertility in non-CBAVD cases. The present study was conducted to estimate the frequency of ΔI507 and ΔF508 CFT...
متن کاملEjaculatory duct obstruction.
PURPOSE OF REVIEW We surveyed the growing literature on ejaculatory duct obstruction and provide suggestions regarding its diagnosis and management. RECENT FINDINGS Ejaculatory duct obstruction is a rare cause of male infertility. With the advent of the high resolution transurethral ultrasound (TRUS) technology, there has been an increase in diagnosis of this disorder. As for the treatment, i...
متن کاملSimultaneous computed tomography and seminal vesiculography in a patient with ejaculatory duct obstruction.
A 32-year-old man presented with primary infertility. He had azoospermia with low volume ejaculate. Physical examination was normal. Transrectal ultrasonography (TRUS) revealed grossly dilated seminal vesicles. No other genitourinary tract abnormality was noted. He underwent TRUS-guided aspiration of the seminal vesicles with simultaneous instillation of contrast media and methylene blue dye in...
متن کاملTransrectal US-guided seminal vesicle aspiration in the diagnosis of partial ejaculatory duct obstruction.
There has been recent interest in techniques for diagnosing ejaculatory duct obstruction (EDO), especially when the partial form of the disease is suspected clinically. Currently, there is no gold standard technique for diagnosing EDO. Transrectal ultrasonography (TRUS), which is the technique used most widely, can overdiagnose EDO. As adjunctive diagnostic techniques, duct chro...
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ژورنال
عنوان ژورنال: The American Journal of Human Genetics
سال: 1997
ISSN: 0002-9297
DOI: 10.1086/301606